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Since its establishment, the Department of Preventive Medicine and Public Health, School of Medicine Keio University has aimed to promote both evidence-based medical research and practices that impact public health. Our mission is to contribute to the development of society through a series of public health activities and the advancement of medical research. We continue to enhance research activities and widely disseminate and return the scientific knowledge obtained through research to society.
We aim to realize precision medicine and precision health by comprehensively collecting and analyzing a wide range of health information, from lifestyle factors to biometric data, to provide prevention tailored to individual characteristics.
As a core project, the Tsuruoka Metabolomics Cohort Study (TMCS) was launched in 2012 and is currently ongoing. With the cooperation of 11,002 Tsuruoka citizens, we are conducting multi-omics analysis of biological samples such as metabolomes and genomes to search for new biomarkers focusing on biological mechanisms, including the interaction between genetic and environmental factors. Sub-studies are being conducted since 2018: TMCS-HTP, which provides evidence of heated tobacco products; TMCS-Aging, which provides evidence of healthy longevity; and TMCS-Women's Health, which provides evidence of women's health.
Ongoing project: Tsuruoka Metabolomic Cohort study (TMCS)
Our department is actively engaged in cohort studies and community awareness research targeting cardiovascular diseases and lifestyle-related diseases. Many of our research findings have contributed to the development of medical practice guidelines and planning by the Ministry of Health, Labour and Welfare in Japan.
Ongoing projects are as follows:
-EPOCH-JAPAN (Integrated Database Collaborative Study of Cardiovascular Epidemiology Cohort Studies)
Using big data of 17 cohorts of 2.5 million person-years, we evaluate risk factors for lifestyle-related diseases and examining models for predicting disease onset.
-The KOBE Study: An urban cohort study using daily health as an indicator
Healthy citizens with no history of illness or treatment are being followed for changes in quality of life.
An educational study of citizens to promote appropriate medical examination behavior at the onset of stroke
We evaluate methods and their effectiveness of awareness-raising activities in communities and schools.
-NIPPON DATA (National Integrated Project for Prospective Observation of Non-communicable Disease And its Trends in the Aged)
A follow-up study of the recipients of the Basic Survey on Cardiovascular Diseases (National Health and Nutrition Examination Survey) conducted by the Ministry of Health, Labour and Welfare of Japan.
-Guidelines, policies, etc. reflecting research results:
Japanese Society of Arteriosclerosis, Japanese Society of Hypertension, Japanese Geriatrics Society
Ministry of Health, Labour and Welfare. Healthy Japan 21 (the second term)
Ministry of Health, Labour and Welfare. Standard Health Examination and Health Guidance Program (FY 2008)
Occupational medicine focuses on supporting the health of working people through prevention and treatment of work-related diseases and injuries as well as increasing productivity and social adjustment in the workplace. In this department, we conduct research on health services to enable the optimal delivery of occupational health services. We are also engaged in research on women’s health to support the health of working women, in response to the increase in the number of working women in Japan.
Environmental and occupational health is becoming increasingly important from a global perspective as represented by the Sustainable Development Goals (SDGs). From this perspective, we are promoting epidemiological research on the effects of chemical substances and the environment on human health, as well as research and practices related to risk assessment, risk management, and risk communication of chemical substances.
Ongoing projects are as follows:
-Indium cohort study
-Epidemiological study of occupational bladder cancer caused by orthotoluidine and other aromatic amines
-Cohort study on lung development in children due to fine particulate matter (PM2.5)
We conduct research on causality methodologies, various bias adjustment methods, and handling of missing values, which are important for epidemiological and clinical research. In addition, we support and promote epidemiological and clinical research in collaboration with various departments and clinical departments within Keio University as well as with external organizations through planning of research design and statistical analysis.
The department is in charge of lectures at the Graduate School of Medicine and the Graduate School of Health Management at Keio University. Through education, we are committed to fostering future public health professionals with expertise in research design and biostatistics.
Yasunori Sato https://k-ris.keio.ac.jp/html/100002103_en.html
Senior Assistant Professor
Concurrent Associate Professor